Gene description for CD81 |
Gene name |
CD81 molecule |
Gene symbol |
CD81 |
Other names/aliases |
CVID6 S5.7 TAPA1 TSPAN28 |
Species |
Homo sapiens |
Experiment description of studies that identified CD81 in Breast milk |
1
|
Experiment ID | 46 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting FACS Mass spectrometry
|
PubMed ID |
17641064
|
Organism | Homo sapiens |
Experiment description | Exosomes with immune modulatory features are present in human breast milk. |
Authors | Admyre C, Johansson SM, Qazi KR, FiléJJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year | 2007 |
Sample | Breast milk |
Sample name | Breast milk - colostrum |
Isolation/purification methods | Differential centrifugation Filtration Sucrose density gradient |
Flotation density | 1.10-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QSTAR] Western blotting Immunoelectron microscopy FACS |
EV-TRACK |
-
|
|
|
2
|
Experiment ID | 48 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting FACS Mass spectrometry
|
PubMed ID |
17641064
|
Organism | Homo sapiens |
Experiment description | Exosomes with immune modulatory features are present in human breast milk. |
Authors | Admyre C, Johansson SM, Qazi KR, FiléJJ, Lahesmaa R, Norman M, Neve EP, Scheynius A, Gabrielsson S |
Journal name |
JIMMU
|
Publication year | 2007 |
Sample | Breast milk |
Sample name | Breast milk - mature milk |
Isolation/purification methods | Differential centrifugation Filtration Sucrose density gradient |
Flotation density | 1.10-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry [QSTAR] Western blotting Immunoelectron microscopy FACS |
EV-TRACK |
-
|
|
|
3
|
Experiment ID | 124 |
Identified molecule | protein
|
Extracellular vesicle type | Exosomes |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
21235781
|
Organism | Homo sapiens |
Experiment description | Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages. |
Authors | Läer C, Alikhani VS, Ekströ, Eldh M, Paredes PT, Bossios A, Sjöand M, Gabrielsson S, Löll J, Valadi H. |
Journal name |
JTM
|
Publication year | 2011 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | FACS Immunoelectron microscopy Western blotting |
EV-TRACK |
EV110029: EV-METRIC:14%, 29%, 14%
|
|
|
4
|
Experiment ID | 173 |
Identified molecule | protein
|
Extracellular vesicle type | Microvesicles |
MISEV | EVs |
Identification method | Western blotting
|
PubMed ID |
21859146
|
Organism | Homo sapiens |
Experiment description | Identification of a conserved glycan signature for microvesicles |
Authors | Batista BS, Eng WS, Pilobello KT, Hendricks-MuñKD, Mahal LK |
Journal name |
J Proteome Res
|
Publication year | 2011 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Filtration Ultracentrifugation |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
EV110033: EV-METRIC:11%, 13%
|
|
|
5
|
Experiment ID | 574 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry [LTQ-Orbitrap Elite, Q-Exactive]
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components |
Authors | Van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
MCP
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Breast milk - normal |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
6
|
Experiment ID | 950 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D1 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
7
|
Experiment ID | 951 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D2 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
8
|
Experiment ID | 952 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D3 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
9
|
Experiment ID | 953 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D4 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
10
|
Experiment ID | 954 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D5 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
11
|
Experiment ID | 955 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D6 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
12
|
Experiment ID | 956 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - D7 |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry Western blotting |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
13
|
Experiment ID | 957 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | EVs |
Identification method | Mass spectrometry
|
PubMed ID |
27601599
|
Organism | Homo sapiens |
Experiment description | Comprehensive Proteomic Analysis of Human Milk-derived Extracellular Vesicles Unveils a Novel Functional Proteome Distinct from Other Milk Components. |
Authors | van Herwijnen MJ, Zonneveld MI, Goerdayal S, Nolte-'t Hoen EN, Garssen J, Stahl B, Maarten Altelaar AF, Redegeld FA, Wauben MH |
Journal name |
Mol Cell Proteomics
|
Publication year | 2016 |
Sample | Breast milk |
Sample name | Milk - derived EVs - pooled |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Density gradient centrifugation |
Flotation density | 1.12-1.18 g/mL |
Molecules identified in the study | Protein |
Methods used in the study | Mass spectrometry |
EV-TRACK |
EV160000: EV-METRIC:50%
|
|
|
14
|
Experiment ID | 2212 |
Identified molecule | protein
|
Extracellular vesicle type | Extracellular vesicles |
MISEV | Small EVs |
Identification method | Western blotting
|
PubMed ID |
37043568
|
Organism | Homo sapiens |
Experiment description | Milk-derived extracellular vesicles protect intestinal barrier integrity in the gut-liver axis |
Authors | Tong L, Zhang S, Liu Q, Huang C, Hao H, Tan MS, Yu X, Lou CKL, Huang R, Zhang Z, Liu T, Gong P, Ng CH, Muthiah M, Pastorin G, Wacker MG, Chen X, Storm G, Lee CN, Zhang L, Yi H, Wang JW. |
Journal name |
Sci Adv
|
Publication year | 2023 |
Sample | Breast milk |
Sample name | Colostrum |
Isolation/purification methods | Differential centrifugation Ultracentrifugation Centrifugal ultrafiltration |
Flotation density | - |
Molecules identified in the study | Protein |
Methods used in the study | Western blotting |
EV-TRACK |
-
|
|
|